Premature rupture of membranes (PROM) is a significant complicating factor in contemporary obstetric practice. It occurs in up to 10% of deliveries1 and is the cause of 10% of all perinatal deaths.2
ROM Plus Fetal Membranes Rupture Test is a rapid, qualitative test for the in vitro detection of amniotic fluid in vaginal secretions of pregnant women. It looks for both Placenta Protein 12 (PP12) and Alpha-Fetoprotein (AFP).
1Mead PB: Management of the patient with premature rupture of the membrane. Clin Perinatol 7:243, 1980 AND Gibbs RS, Blanco JD: Premature rupture of the membranes. Obstet Gynecol, 60:671, 1982
2Naeye RL: Causes of perinatal morbidity in US Collaborative Perinatal Project. JAMA 238:228, 1977
Warning: The test may report positive results in patients with intact membranes and therefore decisions to induce labor should not be based solely on the ROM Plus test results.